Design of experiments#

Tools to help with design of experiments.

nskinetics.doe.fim.optimal_design(rxn_sys, ...)

Perform design of experiments by exhaustively evaluating combinations of initial concentrations and optional spike conditions, returning those that maximize parameter identifiability.

nskinetics.doe.fim.get_sensitivities(...[, ...])

Compute finite-difference sensitivities of ReactionSystem outputs with respect to kinetic parameters.

nskinetics.doe.fim.fisher_information_matrix(...)

Compute the Fisher Information Matrix (FIM) from a sensitivity matrix.

nskinetics.doe.fim.d_optimality(FIM)

Compute the D-optimality score of a Fisher Information Matrix.
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